Professor John Stamatoyannopoulos
Genome Sciences, School of Medicine, University of Washington, USA
Leslie Lazarus Oration:
Gene regulation and common disease
Professor John Mattick
Garvan Institute of Medical Research
Genomic Intelligence
Dr Tim Mercer
Institute of Molecular Biosciences, University of Queensland
Untangling the human transcriptome
We have entered an incredibly exciting new era of discovery. The Human Genome Project has uncovered a wealth of new information about the structure of the genome, the nature of gene expression, and the molecular underpinnings of disease. This information has transformed how we understand human evolution and development, as well as investigate complex disorders.
A totally unexpected discovery was the identification of a complex repertoire of RNA molecules that are critically involved in the regulatory networks that determine cell function and cell fate. But only the tip of the iceberg has yet been revealed.
With the advent of next generation sequencing technologies that permit whole genome, exome, epigenome and transcriptome analyses, new data is being generated at an exponential rate. Computational technologies needed to make sense of this data are also evolving rapidly. It’s a continually changing scene.
The three speakers in this symposium have each made significant contributions to the advances of recent years. They will open a window to showcase some surprising discoveries, and talk about what the future may hold.
This new era in genomic science is currently having, and will continue to have, a major impact on all aspects of research in the life sciences. We invite you to come and learn, and to find out how you might participate in this new journey of discovery.
For more info contact Gabriella O’Neil
t: 02 9295 8120 or e: g.oneil@garvan.org.au